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group c member 1  (Proteintech)


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    Structured Review

    Proteintech group c member 1
    Group C Member 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 129 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/group c member 1/product/Proteintech
    Average 94 stars, based on 129 article reviews
    group c member 1 - by Bioz Stars, 2026-02
    94/100 stars

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    Proteintech group c member 1
    Group C Member 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Proteintech group c member 2 nr3c2
    Fig. 3. Expression of the mineralocorticoid receptor <t>(NR3C2)</t> in the epithelium of the ocular surface: Immunoblotting analysis of NR3C2 using TKE2 cells (a). Immunohistochemical images including conjunctiva, limbus, and peripheral cornea (b). Sections of limbus (c), central cornea (d) and conjunctiva (e) from syngeneic control mice and cGVHD mice treated with vehicle or spironolactone eyedrops were stained for a mineralocorticoid marker NR3C2 (red) (n = 5–7 per group). Data are presented as the mean ± standard error of the mean. *P < .05, based on the Kruskal–Wallis test with Dunn’s post-hoc test., Scale bar, 50 μm.
    Group C Member 2 Nr3c2, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Fig. 3. Expression of the mineralocorticoid receptor (NR3C2) in the epithelium of the ocular surface: Immunoblotting analysis of NR3C2 using TKE2 cells (a). Immunohistochemical images including conjunctiva, limbus, and peripheral cornea (b). Sections of limbus (c), central cornea (d) and conjunctiva (e) from syngeneic control mice and cGVHD mice treated with vehicle or spironolactone eyedrops were stained for a mineralocorticoid marker NR3C2 (red) (n = 5–7 per group). Data are presented as the mean ± standard error of the mean. *P < .05, based on the Kruskal–Wallis test with Dunn’s post-hoc test., Scale bar, 50 μm.

    Journal: The ocular surface

    Article Title: Mineralocorticoid receptor expression and the effects of the mineralocorticoid receptor antagonist spironolactone in a murine model of graft-versus-host disease.

    doi: 10.1016/j.jtos.2024.10.004

    Figure Lengend Snippet: Fig. 3. Expression of the mineralocorticoid receptor (NR3C2) in the epithelium of the ocular surface: Immunoblotting analysis of NR3C2 using TKE2 cells (a). Immunohistochemical images including conjunctiva, limbus, and peripheral cornea (b). Sections of limbus (c), central cornea (d) and conjunctiva (e) from syngeneic control mice and cGVHD mice treated with vehicle or spironolactone eyedrops were stained for a mineralocorticoid marker NR3C2 (red) (n = 5–7 per group). Data are presented as the mean ± standard error of the mean. *P < .05, based on the Kruskal–Wallis test with Dunn’s post-hoc test., Scale bar, 50 μm.

    Article Snippet: This process was applied to antibodies against nuclear receptor subfamily 3 group C member 2 (NR3C2) (21854-1-AP, Proteintech, Rosemont, IL), allophycocyanin-labeled CD45 (103112, 30-F11, BioLegend, San Diego, CA), heat shock protein 47 (HSP47) (ADI-SPA-470-F, M16.10A1, Enzo Life Science, Farmingdale, NY), and fluorescein isothiocyanate-labeled CD4 (100510, RM-4-5, Biolegend).

    Techniques: Expressing, Western Blot, Immunohistochemical staining, Control, Staining, Marker

    Fig. 4. Colocalization of heat shock protein 47 (HSP47) and mineralocorticoid receptor (NR3C2) in the eyelids of chronic graft-versus-host disease (cGVHD) mice: Eyelid and conjunctival sections from the syngeneic control mice and the cGVHD mice treated with vehicle or spironolactone (n = 5–8, per group) were double- stained for HSP47 (green) and NR3C2 (red) (white arrowheads indicate HSP47+ NR3C2+ cells) (a–c). Immunoblotting analysis of NR3C2 using cultured fibro blast derived from the eyelid in a cGVHD mouse (d). IL-6 levels of the culture medium of fibroblast derived from the eyelid of a cGVHD mouse were analyzed using enzyme-linked immunosorbent assays (e). Data are presented as the mean ± standard error of the mean. *P < .05, **P < .01, ***P < .001, based on the Kruskal–Wallis test with Dunn’s post-hoc test or Mann- Whitney U test. Scale bar, 50 μm. HSP47, heat shock protein 47.

    Journal: The ocular surface

    Article Title: Mineralocorticoid receptor expression and the effects of the mineralocorticoid receptor antagonist spironolactone in a murine model of graft-versus-host disease.

    doi: 10.1016/j.jtos.2024.10.004

    Figure Lengend Snippet: Fig. 4. Colocalization of heat shock protein 47 (HSP47) and mineralocorticoid receptor (NR3C2) in the eyelids of chronic graft-versus-host disease (cGVHD) mice: Eyelid and conjunctival sections from the syngeneic control mice and the cGVHD mice treated with vehicle or spironolactone (n = 5–8, per group) were double- stained for HSP47 (green) and NR3C2 (red) (white arrowheads indicate HSP47+ NR3C2+ cells) (a–c). Immunoblotting analysis of NR3C2 using cultured fibro blast derived from the eyelid in a cGVHD mouse (d). IL-6 levels of the culture medium of fibroblast derived from the eyelid of a cGVHD mouse were analyzed using enzyme-linked immunosorbent assays (e). Data are presented as the mean ± standard error of the mean. *P < .05, **P < .01, ***P < .001, based on the Kruskal–Wallis test with Dunn’s post-hoc test or Mann- Whitney U test. Scale bar, 50 μm. HSP47, heat shock protein 47.

    Article Snippet: This process was applied to antibodies against nuclear receptor subfamily 3 group C member 2 (NR3C2) (21854-1-AP, Proteintech, Rosemont, IL), allophycocyanin-labeled CD45 (103112, 30-F11, BioLegend, San Diego, CA), heat shock protein 47 (HSP47) (ADI-SPA-470-F, M16.10A1, Enzo Life Science, Farmingdale, NY), and fluorescein isothiocyanate-labeled CD4 (100510, RM-4-5, Biolegend).

    Techniques: Control, Staining, Western Blot, Cell Culture, Derivative Assay, MANN-WHITNEY

    Fig. 5. Immunohistochemical findings of NR3C2-positive leukocytes in the eyelids of chronic graft-versus-host disease (cGVHD) mice. Sections of the eyelids from the syngeneic control and cGVHD mice treated with vehicle or spironolactone eyedrops were double-stained for NR3C2 (red) and CD45 (white) (n = 5–8 per group). Data are presented as the mean ± standard error of the mean, **P < .01, ***P < .001, based on the Kruskal–Wallis test with Dunn’s post-hoc test. Scale bar, 50 μm.

    Journal: The ocular surface

    Article Title: Mineralocorticoid receptor expression and the effects of the mineralocorticoid receptor antagonist spironolactone in a murine model of graft-versus-host disease.

    doi: 10.1016/j.jtos.2024.10.004

    Figure Lengend Snippet: Fig. 5. Immunohistochemical findings of NR3C2-positive leukocytes in the eyelids of chronic graft-versus-host disease (cGVHD) mice. Sections of the eyelids from the syngeneic control and cGVHD mice treated with vehicle or spironolactone eyedrops were double-stained for NR3C2 (red) and CD45 (white) (n = 5–8 per group). Data are presented as the mean ± standard error of the mean, **P < .01, ***P < .001, based on the Kruskal–Wallis test with Dunn’s post-hoc test. Scale bar, 50 μm.

    Article Snippet: This process was applied to antibodies against nuclear receptor subfamily 3 group C member 2 (NR3C2) (21854-1-AP, Proteintech, Rosemont, IL), allophycocyanin-labeled CD45 (103112, 30-F11, BioLegend, San Diego, CA), heat shock protein 47 (HSP47) (ADI-SPA-470-F, M16.10A1, Enzo Life Science, Farmingdale, NY), and fluorescein isothiocyanate-labeled CD4 (100510, RM-4-5, Biolegend).

    Techniques: Immunohistochemical staining, Control, Staining

    Fig. 6. Immunohistochemical findings of NR3C2-positive T cells in the conjunctiva of chronic graft-versus-host disease (cGVHD) mice. Sections of the eyelids from syngeneic control mice and cGVHD mice treated with vehicle or spironolactone eyedrops were double-stained for NR3C2 (red) and CD4 (green) (n = 5–8 per group). Data are presented as the mean ± standard error of the mean. **P < .01, based on the Kruskal–Wallis test with Dunn’s post-hoc test. Scale bar, 50 μm.

    Journal: The ocular surface

    Article Title: Mineralocorticoid receptor expression and the effects of the mineralocorticoid receptor antagonist spironolactone in a murine model of graft-versus-host disease.

    doi: 10.1016/j.jtos.2024.10.004

    Figure Lengend Snippet: Fig. 6. Immunohistochemical findings of NR3C2-positive T cells in the conjunctiva of chronic graft-versus-host disease (cGVHD) mice. Sections of the eyelids from syngeneic control mice and cGVHD mice treated with vehicle or spironolactone eyedrops were double-stained for NR3C2 (red) and CD4 (green) (n = 5–8 per group). Data are presented as the mean ± standard error of the mean. **P < .01, based on the Kruskal–Wallis test with Dunn’s post-hoc test. Scale bar, 50 μm.

    Article Snippet: This process was applied to antibodies against nuclear receptor subfamily 3 group C member 2 (NR3C2) (21854-1-AP, Proteintech, Rosemont, IL), allophycocyanin-labeled CD45 (103112, 30-F11, BioLegend, San Diego, CA), heat shock protein 47 (HSP47) (ADI-SPA-470-F, M16.10A1, Enzo Life Science, Farmingdale, NY), and fluorescein isothiocyanate-labeled CD4 (100510, RM-4-5, Biolegend).

    Techniques: Immunohistochemical staining, Control, Staining